Search results for "Rat duodenum"
showing 2 items of 2 documents
Essential oil of Sicilian Prangos ferulacea (L.) Lindl. and its major component, β−ocimen, affect contractility in rat small and large intestine
2023
Ethnopharmacological relevance: Prangos ferulacea (L.) Lindl is an Apiaceae plant, widely used in traditional medicine. Recently, chemical composition and biological activities of its essential oil (Prangroil) have been reported, but there are no studies on possible effects on intestinal contractility. Aims of the study: We investigated the effects of essential oil Sicilian Prangoil on the contractility of rat small (duodenum) and large (colon) intestine and the related action mechanism. Materials and methods: Responses to Prangoil and to its major component β-ocimen in intestinal segments were assessed in vitro as changes in isometric tension. Results: Prangoil, induced in duodenum, depend…
Effects ofThymus species extracts on rat duodenum isolated smooth muscle contraction
1989
The diethylether, ethylacetate and butanolic extracts from Thymus webbianus and Thymus leptophyllus were tested for spasmolytic activity. Pre-incubation of the isolated rat duodenum with these extracts for 10 min produced a concentration-dependent inhibition of acetylcholine-induced contractions. This effect was at least ten times greater with the apolar extracts than with the polar extracts.